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Abruzzi may refer to:
- John Abruzzi, one of the Fox River Eight.
- Abruzzi's Wife, John Abruzzi's wife.
- Abruzzi's Children, John Abruzzi's kids.
- Abruzzi's Mobsters, John Abruzzi's gang of Mafia.
- The Abruzzi Family as a whole.